Central Dogma: Chromosome Project – Day 3

After two days in the computer lab, students should have compiled enough information for their Chromosome Project to complete page 1 of the PowerPoint template (goal #1).  Next, download and complete the Day 3 Activity Log.  The major focus of today is to identify credible scientific resources and find the information necessary to complete slides 2 and 3 of the PowerPoint.

  • Symptoms and characteristics of the disease/condition:
    • How does someone know they have the disease/condition?
    • What body systems are affected and how?
    • What tests are used to detect the disease/condition?
  • Who is affected?  Who is at risk for having the disease/condition
  • Outlook or quality of life:
    • What happens if the disease/condition goes untreated?
    • What treatment options are currently available?
    • How does treatment affect the disease/condition?
    • What treatment options may be available in the future?

Project scoring update: Many students were unable to locate their Day 1 Activity Log files, suggesting a problem with the student drives.  Out of fairness, the grading rubric will be updated as follows:

  • Minimum of 3 Daily Logs: 10 points per log (30 points total)
  • PowerPoint slides (50 points total)
  • Reflection (10 points)
  • Audience participation during presentations (10 points)
  • Presentation of PowerPoint (10 points of extra credit)

Central Dogma: Chromosome Project – Day 2

Students should download and complete the Day 2 Activity Log to document progress on the chromosome project, saving it to their student drive.  Please review the project description and grading rubric by visiting last Thursday’s post.

Ready to research a specific gene?  Head over to the NCBI Human Genome Resources page and enter your gene name into the “Find a Gene” box on the left panel.  Be sure to select “homo sapiens” in the pull-down box.  When the search completes, click on your gene name (typically the first gene on the list) and browse through the entry.  There is a ton of information provided!  The length of the gene can be found by hovering your mouse over the top green line under the “genomic regions, transcripts, and products” and looking for the number after the word “length.”  The length of the amino acid sequence can be found by clicking on the word “protein” on the right hand side of the page under Related Information.  Browse the entries for the full-length protein and note the number of amino acids in the protein.  The full-length protein can be challenging to find: look for an entry that does not include words like truncated, isoformpredicted, synthetic construct, or unnamed protein product.